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Overview

Bioinformatics Software

 

Category Programs Installation Documentation Updates
Sequence analysis all common tools for
  • similarity search: Blast(NCBI-,WU-,MPI-),BLAT,HMMer ....
  • multiple alignment: ClustalW,Dialign2,Muscle,T-Coffee, ...
  • phylogeny: PhylIP,MrBayes(MPI),BayesPhylogenies,ARB, ...
  • structure prediction: TMHMM, SignalP, PsiPred, Arby, Modeller, ...
* /afs/rzg/bioinfo/biosoft/

(Linux,IBM-AIX,SUN-Solaris)
/afs/rzg/bioinfo/biosoft/<tool name>/... regular updates
MIGenAS toolkit: integrated sequence analysis
(web application + SOAP web sevices)
http://www.migenas.mpg.de
http://www.migenas.org
online, published in NAR actively developed, regular updates
Genome annotation GenDB 2.2: a tool for automatic and manual annotation of prokaryotic genomes

https://www.bioinfo.mpg.de/gendb22 (GenDB 2.2)

published in NAR bugfixes
HaloLex: comprehensive annotation and information system for prokaryotic genome and proteome data http://www.halolex.mpg.de online actively developed by MPI of Biochemistry and RZG
Genome Assembly consed, parallel portable Linux version of phrap and crossmatch, on request on request -
Visualization Tree viewers, alignment editors, structure viewers /afs/rzg/bioinfo/soft/visualization/ /afs/rzg/bioinfo/soft/visualization/... regular updates

* /afs/rzg is a shortcut (CellAlias) for /afs/ipp-garching.mpg.de. It is equivalent to /afs/ipp or /afs/ipp-garching.mpg.de/

 

 

Databases

Type Databases Formats Indexes Location Updates
public sequence databases UniProt(swissprot,TrEMBL),nr,nt,pdb,... fasta NCBI blast /bio/db/, /afs/rzg/bioinfo/pub_db/ weekly (Sat)
UniProtKB(swissprot,TrEMBL) XML - /bio/db/XML/uniprot/ biweekly (Sat)
iProClass XML - /bio/db/XML/iProClass/ biweekly (Sat)
completed public genomes >550 prokaryotic strains, ~10 eukaryotic fasta,gbk NCBI blast /bio/db/, /afs/rzg/bioinfo/pub_db/ weekly (Sat)
Protein structures PDB pdb (atom coordinates) - /bio/db/PDB/ weekly (Sat)

 

Dedicated Compute Resources

Besides general resources which are open to all RZG users there are dedicated compute and storage facilities for computational biology projects.

 

IBM Blade Center linux cluster (blade center oe, 28 dual-core Intel 64-bit Woodcrest CPUs) MPI of Biochemistry, MIGenAS
 SUN FIRE linux cluster (eva cluster 128 dual-core AMD 64-bit Opteron CPUs) MPI of Evolutionary Anthropology

 

 

 

 

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